Key Takeaways
- CVS: Most CVS pharmacies will remain open on Thanksgiving, though some may operate on a reduced holiday schedule.
- Walgreens: The majority of Walgreens locations will be closed on Thanksgiving Day. Only its 24-hour stores and pharmacies are expected to remain open.
- Grocery Store Pharmacies: Pharmacies inside major retailers like Walmart, Costco, Kroger, and Target will be closed for the holiday.
- Plan Ahead: Customers are strongly encouraged to call their local store or check hours online before heading out for any last-minute needs.
As families prepare for Thanksgiving on Thursday, November 27, 2025, many are finalizing travel plans and dinner menus. However, a last-minute trip to the pharmacy can sometimes be an unexpected part of the holiday rush. If you need to pick up a prescription or other essentials, it’s crucial to know which stores will be open.
Here’s a breakdown of the Thanksgiving Day hours for major pharmacy chains like CVS and Walgreens.
CVS Holiday Hours
CVS will be a reliable option for many, as the company confirmed its pharmacies will be open on Thanksgiving.
However, a spokesperson noted that some locations might have adjusted or reduced hours to accommodate the holiday. To avoid any inconvenience, it is best to call your neighborhood CVS directly or verify its operating hours on the official CVS.com store locator before visiting.
Walgreens Thanksgiving Schedule
Walgreens is taking a different approach this year. The company has stated that most of its locations will be closed on Thanksgiving to allow employees to spend time with their families.
The main exception will be its 24-hour stores and pharmacies, which are scheduled to remain open. For all other non-24-hour locations, the doors will be shut. Customers should use the Walgreens store locator or call ahead to confirm if their nearest pharmacy is one of the few that will be open.
Are Pharmacies in Grocery Stores Open?
If you typically fill your prescriptions at a pharmacy inside a larger retail store, you will need to plan ahead.
Major chains, including Walmart, Costco, Kroger, Sam’s Club, Food Lion, and Target, have confirmed that their in-store pharmacy services will be closed on Thanksgiving Day. While some of these grocery and retail stores may be open, their pharmacy departments will not be operational. Customers are advised to check the specific hours for their local stores but should plan to pick up medications before the holiday.
Image Referance: https://www.usatoday.com/story/money/2025/11/26/pharmacies-cvs-walgreens-open-closed-thanksgiving-2025/87444563007/